Klaus Peter Rentrop

Cardiologist, Medical Director

 Klaus Peter Rentrop has made significant contributions to cardiology, with 2023 marking two notable milestones in his career. First, the 45th anniversary of percutaneous coronary intervention (PCI), a technique he first performed in 1978 to treat heart attacks. PCI has since become the preferred method for managing heart attacks, saving millions of lives worldwide. The second milestone is the 30th anniversary of founding the American Society for Nuclear Cardiology, where he played an integral role as a Founding Member in 1993.


Originally from Cologne, Germany, Dr. Klaus P. Rentrop now calls New York home. His journey in medicine took him from Germany to the United States, where he completed his Cardiology Fellowship at the Cleveland Clinic in 1973. This foundation set the stage for a long and impactful career in cardiology, focusing on advancing patient care and cardiac research.

Shaping the Future of Cardiology

Throughout his career, Klaus Peter has been at the forefront of cardiology, contributing to treating and understanding heart disease. His pioneering work has left an indelible mark on the field, mainly in acute and chronic cardiac care.

Revolutionizing Acute Cardiac Treatment

In 1978, Klaus P. Rentrop introduced percutaneous coronary intervention (PCI), forever changing the way heart attacks are treated. This minimally invasive procedure became a game changer, significantly reducing mortality rates and improving outcomes for heart attack patients. Additionally, in 1979, he played a key role in advancing thrombolytic therapy for acute myocardial infarction, providing an additional tool to improve survival rates in heart attack patients.


His research led to the creation of the Rentrop Collateral Classification in 1985, which remains a widely used system for assessing the collateral circulation in the heart. This classification has become an essential part of cardiology, aiding doctors in diagnosing and managing coronary artery disease.

Advancing Chronic Cardiovascular Care

Klaus Peter Rentrop MD’s contributions to chronic cardiovascular care are equally significant. He helped develop the 0.8mm Spectronetics Laser catheter, which removes atherosclerotic tissue from coronary and peripheral arteries. He also introduced Positron Emission Tomography (PET) to the New York area, a sophisticated imaging technique that has become the gold standard for diagnosing coronary artery disease. PET enables doctors to non-invasively evaluate blood flow to the heart, helping identify dangerous blockages while avoiding unnecessary procedures for less severe cases. This advancement has improved patient care and reduced healthcare costs by minimizing the need for invasive surgeries.

A Leader in Service

Beyond his groundbreaking clinical and academic work, Klaus Peter is known for his strong sense of social responsibility. He dedicated significant personal resources to making advanced cardiac care accessible to underserved communities. By contributing $8.5 million from his patent royalties and seven-year salary, he ensured cardiac PET technology could reach those in need, demonstrating his commitment to improving healthcare for all.

A Life of Balance

Dr. Klaus P. Rentrop also values a well-rounded life. He enjoys meditative walking, swimming, chess, and reading outside his professional work. These hobbies reflect his commitment to personal growth and maintaining a balanced, thoughtful approach to life.


Klaus Peter Rentrop’s lasting impact on cardiology and unwavering dedication to helping others have solidified his legacy as a medical and community leader. His work continues to inspire, and his compassionate approach to healthcare sets a standard for others to follow.